The discovery of the lac operon, François Jacob

Interviewee: François Jacob. François Jacob talks about how enzyme production was viewed at the time they were beginning their experiments. (DNAi Location: Code > Controlling the code > Players > François Jacob and Jacques Monod > Induction vs. adaptation)

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15272. The molecular biology of the lac operon, Fraois Jacob

François Jacob talks about the relationship between DNA, ribosomes, and protein production.

  • ID: 15272
  • Source: DNAi

15270. Deciding on studying the lac operon, François Jacob

François Jacob explains why Jacques Monod chose to work with the lactose system.

  • ID: 15270
  • Source: DNAi

15271. Discovering the lac operon, François Jacob

François Jacob talks about bacterial mutants that could not metabolize lactose. Using these mutants, Jacob and Monod figured out how protein production is controlled.

  • ID: 15271
  • Source: DNAi

16688. Animation 33: Genes can be turned on and off.

Jacques Monod and François Jacob work with how bacteria breaks large sugars into smaller pieces.

  • ID: 16688
  • Source: DNALC.DNAFTB

16703. Problem 33: Genes can be turned on and off.

Learn more about the lac operon system.

  • ID: 16703
  • Source: DNALC.DNAFTB

15276. Genes control the structure of proteins, François Jacob

François Jacob talks about Genes control the structure of proteins

  • ID: 15276
  • Source: DNAi

15274. The production of messenger RNA, François Jacob

François Jacob, Sydney Brenner and Matt Meselson worked on the role of mRNA. An on/off switch involving mRNA seemed a logical control point for protein production.

  • ID: 15274
  • Source: DNAi

15253. Discovering the lac operon, Walter Gilbert

Walter Gilbert talks about identifying the lac operon repressor.

  • ID: 15253
  • Source: DNAi

15268. Designing bacteria, François Jacob

François Jacob talks about designing bacteria.

  • ID: 15268
  • Source: DNAi

15884. The lac operon

Francois Jacob and Jaçques Monod figured out how bacteria controlled the production of an enzyme called beta-galactosidase. This system of feedback and negative regulation became the lac operon and was the first model for the control of protein productio

  • ID: 15884
  • Source: DNALC.DNAi